ea0011s99 | Metabolic syndrome | ECE2006
Savage DB
Insulin resistance, which can be defined as a state of reduced responsiveness to normal circulating levels of insulin, plays a major role in the development of type 2 diabetes. Whilst standard definitions of insulin resistance still define it in terms of insulins effects on glucose metabolism, the last decade has seen a shift from the traditional glucocentric view of diabetes to an increasingly acknowledged lipocentric viewpoint. This hypothesis h...